Review of Galantamine Stacked with Choline Bitartrate

galantamine choline bitartrateUsing Galantamine and Choline together has become a popular combination for stimulating lucid dreams, but the combination can also offer dramatic improvements in memory, concentration, and mental clarity. Galantamine and Choline affect similar pathways in the brain and combining the two improves the transmission of Acetylcholine in the brain more than either of them alone. Supplement stores such as GNC carry supplements containing both Galantamine and Choline to improve your quality of sleep and enhance your dreams.

Galantamine6 mg x 30 capsules
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Galantamine – How it works

Galantamine is plant-derived alkaloid compound extracted primarily from Galanthus Caucasicus, or Caucasian Snowdrop, as well as certain species of Narcissus and Lycoris. Galantamine was discovered and first studied in the Soviet Union in the 1950s. It was first synthesized in Bulgaria in 1959.

The popularity of Galantamine spread throughout Russian countries, then across Eastern Europe. It has been used in Eastern Europe as a treatment for a variety of cognitive conditions such as Alzheimer’s, and sensorimotor conditions such as myasthenia, myopathy, and sensorimotor conditions arising from the central nervous system. It has also gained popularity as a nootropic thanks to its ability to improve memory and concentration.

It didn’t take long for users to notice that Galantamine sharpened their visual perception, made colors more vivid, stimulated more detailed dreams that were more easily recalled, and stimulated lucid dreams.

Effects on Acetylcholine

Galantamine works by inhibiting the function of Acetylcholinesterase, an enzyme responsible for mopping up used Acetylcholine molecules. Acetylcholine is a neurotransmitter that transmits signals in the brain that deal with perception, reasoning, and the formation and recall of memories. Acetylcholine is released by a neuron, crosses a synapse, and binds with a receptor on the next neuron to communicate messages. As soon as the chemical message has been passed, the role of Acetylcholine is done, and ready to be broken down by Acetylcholinesterase so that it can be recycled.

By blocking some of the effects of Acetylcholinesterase, Galantamine increases the amount of Acetylcholine in the synaptic spaces, increasing the rate of neurotransmission. This allows for memories to be more easily formed, consolidated, and recalled, heightened cognitive activity, and enhancement of the part of the brain that produces dreams. This last is credited for increasing the vividness of dreams and an increase in lucid dreaming among users.

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Stacking Galantamine with Choline

Adding Choline can create a synergy with Galantamine. Choline is classified as a B vitamin and is found in many common foods. Choline isn’t used solely in the brain; it is also used to transport fats throughout the body so it can be used for fuel, and to help build and cell membranes in the entire body. In the brain, the cell membranes are vital to the transmission of nerve signal and for regulating the rate at which chemicals, nutrients, and waste enter and leave the cells.

For all the work choline does in the body, its primary function is as a precursor to Acetylcholine. If you aren’t getting enough choline in your diet, you may end up with insufficient Acetylcholine in your brain. It’s estimated that 90% of the population is not getting enough choline, which may be a large contributor to Alzheimer’s disease and other age related cognitive issues. Simply getting more choline in your diet can increase your Acetylcholine levels, increasing your focus and memory, and stimulating lucid dreaming.

Adding Choline Bitartrate to Galantamine

Choline and Galantamine complement each other by working on opposite sides of the Acetylcholine equation. Because Choline is used to synthesize Acetylcholine, and Galantamine slows the breakdown of Acetylcholine, there is a synergy between the two supplements that dramatically increases cognitive processing, improves learning ability, extends attention span, and overall better brain health. In the US, the combination is used as a clinical treatment of Alzheimer’s disease, as it is thought to slow the progression of the disease and help patients think more clearly.

Despite all these advantages of Galantamine and Choline, many users are more interested in the supplements for inducing lucid dreams. The pharmaceutical companies that produce these supplements are offering products containing both supplements, though this can end up costing you a bit more, especially if you buy a name brand product. If you want to save a little money, you can buy the two supplements separately and create your own stack.

Safe Dosing Suggestions

Most experts recommend a dose of 4-20 mg of Galantamine per day. If you are planning to Galantamine and Choline together, you may want to start at the low end of the spectrum, as it should take less to produce results when the supplements are used in combination. The recommended dose of Choline is 200-300 mg per day. The timing of your dose depends on what you hope to achieve. If you are seeking lucid dreams, you would take your daily dose all at once in the middle of the night, after sleeping a few hours.

This can help minimize sleep disruptions and nightmares. If you are studying or otherwise want to maintain focus over a long period of time, you may want to split your daily dose and take it twice.

Possible Stack Side Effects

Both Galantamine and Choline are generally safe and rarely cause serious side effects in healthy adult users, though in rare cases either one can cause an allergic reaction. If you start to develop hives, rash, redness, or swelling, especially swelling of your face or tongue, discontinue use and get medical attention. In some cases, users may experience more mild side effects, including upset stomach, dizziness, headache, or anxiety. Adjusting your ratio of Galantamine to Choline should alleviate these side effects.

When you take the supplements may also influence whether you experience side effects. In some users, taking Galantamine and Choline just before going to sleep can lower sleep quality and can lead to vivid dreams and possibly nightmares. To minimize this, it is recommended that you sleep for about 5 hours, wake up and take the supplement, and then go back to sleep in a strategy sometimes referred to as a Wake-Back-To-Bed dose.


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