Galantamine Review, Effects and How it Works

galantamine review
Galantamine is a natural alkaloid, first derived from the flowers of the Galanthus Caucasius plant. The synthetic formulation was developed in 1959 in Bulgaria. Since that time it’s been routinely used throughout Europe in treating a lot of different motor and sensory disorders including myasthenia and myopathy. Galantamine is also very popular as a nootropic supplement to enhance intelligence and to improve memory. The United States Food and Drug Administration (FDA) has approved Galantamine to treat Alzheimer’s disease. You can buy it over the counter formulated as a supplement or in the form of a prescription medication, depending on your use.

Galantamine6 mg x 30 capsules
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The Effects of Galantamine

It is widely thought that Galantamine performs dual actions. It first blocks certain enzymes and their activities in the brain. Galantamine acts as an acetylcholinesterase inhibitor, preventing the breakdown of the neurotransmitter acetylcholine in the brain.

Acetylcholine is vital to the transmission of important signals in the brain. These involve cognition, attention and memory. As we age, the levels of acetylcholine naturally subside and therefore their activity becomes lower. In people suffering from Alzheimer’s and other types of senility and cognitive decline, their acetylcholine brain activity is very low. By bringing about a moderate increase in the levels of acetylcholine in the brain with Galantamine, people suffering from these cognitive impairments can increase their clarity of thought and overall mental performance.

The second part of the dual action of Galantamine has to do with modulating the nicotinic receptors on the surface of brain cells. These receptors are vitally important as synaptic sites that respond to, not just acetylcholine, but other chemicals as well, including nicotine, thus the name. Galantamine changes these receptors to protect and preserve their quantity and their functionality.

Brain Benefits of Galantamine

The main benefit of using Galantamine is to enhance cognitive ability, which is what nootropic supplements do. Increasing the levels of acetylcholine in the brain is key to the enhancement, as this particular neurotransmitter is believed to play a critical role in learning and memory. Many users report an increase in their ability to form memories, an increased capacity for learning, a longer and more focused attention span, and improved ability to concentrate. Some people have reported enhanced sensory perception in that they seem to see colors as much brighter and sounds seem sharper.

Galantamine also seems to have some beneficial effects on sleep. There are reviews that report that the supplement helps in falling asleep as well as producing a sounder sleep with a feeling of being more refreshed upon awakening. This is very beneficial for those suffering from sleep disorders or insomnia.

A very interesting effect of Galantamine is that it seems to help users have what’s called “lucid dreams.” These occur when the person is asleep and aware that they are dreaming. Many consider this beneficial. Even if you don’t actually have lucid dreams, Galantamine does seem to make dreams clearer and more easily recalled. This is most likely because increasing the levels of acetylcholine can heighten dream activity as well as increase the duration of REM sleep.

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Galantamine Dosages and Usage

What is generally accepted in terms of dosage is somewhere between 4 mg and 24 mg a day. How much you take depends a great deal on what you are using Galantamine for. Someone seeking to have lucid dreams would need to take it during the day as well as at night, with each dose being somewhere from 4 mg and 12 mg. Very rarely would it be acceptable to take the maximum dose of 24 mg of Galantamine in a day.

If you’re using this as a nootropic it is recommended that you start at the lowest dose effective for you and slowly increase it after you become aware of how it’s affecting your body. This supplement is known for building up a tolerance, so you should consider taking it cyclically, giving yourself as much time off the supplement as time using it. This supplement has a pretty long half-life of about 5 to 6 hours. This means you should space out your dosages, taking into consideration what your purpose is for taking the supplement.

Adverse Effects of Galantamine Capsules

This is widely thought to be a very safe supplement and usually well tolerated for most people. But there have been reports of some side effects, which you should try to avoid. If you happen to be allergic to daffodils or their plants, you may be allergic to Galantamine. The side effects that have been commonly reported are nausea, dizziness, loss of appetite, headaches and fatigue. If you experience any kind of allergic reaction, especially hives or some other skin reaction, stop using the supplement immediately and get to a medical professional or physician right away.

Final Galantamine Review

Galantamine is a very effective supplement that produces quite a few nootropic benefits related to learning and memory. There are some known side effects that users have reported, however if you are taking the proper dosage and as directed, you are not likely to suffer any adverse effects. To enhance your levels of acetylcholine even more you may want to add a cholinergic supplement, like Citicoline or Alpha GPC.

Users commonly take their Galantamine along with Racetam nootropics like Anirecetam or Piracetam. In the UK and other countries, a prescription may be needed to buy these compounds in high dosages. If Galantamine is not available at your favourite supplement store, you can try Huperzine A as an alternative. This too is an acetylcholinesterase inhibitor similar to Galantamine, plus it actually is more popular among people using it for nootropic purposes.


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