Galantamine

Galantamine in the United Kingdom Legality & Where to Buy

galantamine ukGalantamine is a natural alkaloid extracted from the flowers of the Galanthus Caucasicus plant. It increases the levels of a powerful neurotransmitter in the brain, acetylcholine by inhibiting its breakdown, a process called acetylcholinesterase. By having more of this neurotransmitter at the synaptic receptors, overall cognitive abilities improve, specifically memory and focus. In the United States, the FDA has approved Galantamine as a treatment for Alzheimer’s disease. This is not a cure, but it has been deemed effective in slowing the progression of the disease for patients who are still in the mild or moderate stages.

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Where to Purchase Galantamine

There are a number of different brand names for the prescription form of Galantamine, which are Lycoremine, Nivalin, Razadyne and Reminyl. In the UK, the drug it is sold under the name Reminyl. This drug requires a prescription from a physician, however its active ingredient is Galantamine Hydrobromide and this is available as a dietary supplement and can be purchased over-the-counter. It is rare that a compound would be available in both prescription form and a non-prescription product simultaneously, it does happen from time to time. In the United Kingdom, Galantamine had been in wide use as a common dietary supplement before a large pharmaceutical company realized its effectiveness. They then repackaged it and began marketing Galantamine to treat specific diseases.

Galantamine Research

Galantamine was first discovered in Russia in the 1950s and studied at length in the Soviet Union. Then researchers in Bulgaria isolated Galantamine, identifying this as the beneficial ingredient among a number of alkaloids contained in a small white flower. Since the end of that decade Galantamine has been effectively used in the treatment of myasthenia, a disorder affecting the neuromuscular system, myopathy a disease causing a weakening of the muscles, as well as other motor and sensory disorders. It is also being widely used as a nootropic due to its ability to improve cognitive functions.

There are two aspects of Galantamine, working together to bring about its nootropic effects. First it inhibits the effects of acetylcholinesterase (AChE), which is the enzyme responsible for breaking down Acetylcholine, a powerful neurotransmitter in the brain. Acetylcholine is needed in order to form memories, stay focused and for learning to take place. When Galantamine acts to inhibit AChE, then the levels of Acetylcholine remain higher for use by the brain. The other aspect of Galantamine that is helpful is that it binds itself to the receptors for Acetylcholine, which improves their receptivity to the neurotransmitter, increasing the response.

Does Galantamine Require a Prescription in the UK?

If you are buying the dietary supplement form of Galantamine you do not need a prescription in the UK. If you are looking for Reminyl, the brand name of the prescription medication, then you would need to have a prescription. This, as mentioned earlier, is because Galantamine was already being widely used as a dietary supplement before it was co-opted by a big pharmaceutical company to treat certain muscular diseases as well as Alzheimer’s. The only noticeable difference between the two forms is that the prescription medication has been formulated into two different products to include time-release coatings. Other than this there doesn’t seem to be any difference between the supplement and the drug, except for the price of course. Reminyl ER is a whole lot more expensive than Galantamine powder.

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Buying Galantamine in the UK

Although Galantamine supplements are legal to use in the UK, this product is very difficult to find inside the country. Many UK residents just go online to a reputable nootropic store, which is located in the U.S. What we recommend is that you order enough to last you 30 to 90 days to make it easier to get the product past customs.

Recommended Dosages

Galantamine is a powerful supplement so the recommended dose is very tiny. If you are new to using Galantamine, start with an extremely small dose so that you can see if there is any allergic reaction. If you are allergic to daffodils, you should avoid Galantamine.

If you don’t have an allergic reaction after testing Galantamine, start by taking 4 mg so that you can feel the effects and experience your system responding to the supplement. Do not increase your dosage until you know how both your body and mind are responding. Most people using the supplement take from 4 mg – 12 mg a day. Users can build up a tolerance to Galantamine with regular use; therefore it is best to use this in cycles. It is important to consult with your physician before using Galantamine to check for any medical condition you might have that would add to the risks or whether you are taking any type of medication that would not interact well with Galantamine. You should not take Galantamine if you are using anything like Huperzine-A, another cholinesterase inhibitor.

Galantamine Dangers and Warnings

There are some side effects that have been reported, but these are rare. They can be mild, such as tiredness, headaches, loss of appetite, dizziness and nausea. Or they can be more serious, like having an allergic reaction and getting hives or rashes, swelling of the lips, mouth or tongue, or black or bloody stools. If you have any of these types of side effects, stop taking Galantamine immediately and see your physician or another medical professional right away.

Galantamine can be purchased in the UK, bot as a dietary supplement without a prescription and as a prescription medication under the brand name Reminyl, which is used in treating mild to moderate cases of Alzheimer’s disease. There doesn’t seem to be any noticeable difference in terms of the active ingredient, Galantamine, between the two forms. Although the prescription medication comes in a time-release coating, which some might prefer. Since Reminyl is very expensive in the UK, many people prefer the supplemental form of Galantamine. People who use this for nootropic purposes usually go online to make their purchase because the availability in the UK is very limited.

References

Galantamine – Nootriment
Wikipedia

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