Alleviate Depression and Improve Mood with Piracetam

piracetam for depression

A nootropic supplement best known for improving learning and memory, Piracetam is also known to improve mood, making it useful in alleviating depression and other mood disorders. A nootropic drug or supplement is one that has been reported to improve mental functions including memory, intelligence, thought processes, motivation and concentration. It is unclear exactly how nootropics work, but it is thought that they may alter the supply of neurochemicals in the brain, oxygen supply to the brain or by stimulating nerve growth. Click here to buy Piracetam online.

The medical journal Drugs published an article in 2010 that reported that Piracetam may actually be more effective in reducing the symptoms of mood disorders than for cognitive function. There are other nootropics that are somewhat more potent than Piracetam for boosting mood, such as Aniracetam which is similar to Piracetam but works a little differently. However, Piracetam is typically considered a better supplement to start with for those who have never used these kind of supplements before.

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What is the Piracetam Drug?

Piracetam is a GABA-derived drug even though it does not interact with GABA receptors. In the 1960s, it was found to enhance cognition by stimulating the muscarinic acetylcholine receptors. These receptors are important in learning and popular with both students seeking good grades and elderly people trying to improve their memory. Piracetam also works to improve blood flow to the brain, improving oxygenation of nerve tissue and brain metabolism. These actions help to improve energy levels, concentration and motivation. Piracetam also acts to protect the nervous system from damage due to stroke, trauma and the aging process.

Piracetam Raises Dopamine

Though Piracetam is most often used to improve cognition and intelligence, it also works to lower anxiety, boost mood and even easing symptoms of depression. Piracetam has been shown to raise dopamine levels. Dopamine is one of the primary neurotransmitters that produces good feelings. People with depression are typically found to have low dopamine levels, which makes this action especially helpful to them.

By improving circulation and oxygenation and metabolism in the brain, Piracetam has also been shown to improve energy levels. Oxygen and glucose are both vital to the function of the brain. Depression is frequently characterized by long-term fatigue, so by improving energy levels in the brain, it is possible to improve alertness and thereby reduce the feelings of fatigue that so often accompany depression.

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Studies on Depression and Anxiety

A number of studies have examined Piracetam’s effects on depression and anxiety. One of these studies found a 32% decrease in depression symptoms in those with dementia and Alzheimer’s. Another study found that Piracetam was especially helpful in managing depression in patients who also had some cerebrovascular disorders. A third study published in the Indian Journal of Experimental Biology found high levels of serotonin in participants taking high doses of Piracetam. Other trials have found actions similar to GABA drugs, which may explain how it can help induce feelings of calm and lower anxiety levels.

Can Piracetam Treat Depression?

Though studies performed on Piracetam to date show that it has great promise in treating depression, the most compelling information on the advantages of Piracetam come from user reviews. While clinical trials and formal studies are generally considered to be better sources of reliable information, anecdotal evidence can also offer a wealth of information into the average user’s experience with Piracetam. The following reviews have been taken from a variety of online forums dedicated to nootropics and other supplements for depression. Keep in mind that nootropics, like all supplements, every different users in different ways. Your results may or may not be similar to those below. Read User Reviews of Piracetam here.

“I noticed my mood was distinctly more stable when taking Piracetam. I noticed that I was oddly cheerful even when under a great deal of stress. I still felt negative feelings from time to time, but they didn’t seem to last as long or to occur quite as often.” – Dr. Chocoholic

“I’ve found that my mood was always annoyed and happier when I take the Piracetam.” – DiabolicScheme

“When I started taking Piracetam, I noticed an increase in both my physical and mental activity levels, reduced fatigue and better sleep. Over time, my relentless mood swings, impulsivity and bad behavior started to vanish. I felt more active, more productive and less sluggish in the morning. I also felt more active and found my symptoms of depression are gone.” – Parapsychiatrist

“Before I found Piracetam, I experienced a lot of swings in my mood, but now I feel a lot more stable.” – 10ftgp

Other Nootropics for Depression

Piracetam has been shown to be an effective antidepressant by itself, but better results can often be achieved with by stacking Piracetam with other nootropics. The idea behind nootropic stacks involves taking multiple nootropic supplements at the same time to create synergy between them. Taking more than one supplement known to improve mood can magnify the benefits of each to get greater results than taking any of them alone. The supplements you choose for your Piracetam stack will depend on what you hope to achieve with them.

A popular compound for stacking with Piracetam is a choline such as Citicoline or Alpha GPC. While there is evidence that cholines may boost the cognitive effects of Piracetam, they have not been shown to improve depression. Perhaps a better choice for depression is to stack Piracetam with other nootropics that are also known to improve mood. What follows is a list of a few supplements that may boost mood when used in conjunction with Piracetam. Check out our complete guide on the best way to take Piracetam.

• Modafinil: Modafinil acts as a stimulant that increases alertness and motivations. This nootropic is frequently taken to raise energy levels when dealing with depression.

Phenibut: One of the most popular nootropics used for anxiety, Phenibut has effects that also work on depression symptoms. Phenibut is a potent GABA agonist that works as a sedative and releases inhibitions.

Picamilon: Similar to Phenibut, but acts as a stimulant rather than a sedative. Users report a sense of well-being and increased energy when taking Picamilon.

Inositol: Related to B vitamins and known to boost the ability of GABA to inhibit certain neurotransmitter levels. Increases in GABA are linked to feelings of relaxation and calm. Alcohol works in a similar manner, by binding to GABA receptors.

Sulbutiamine: Also related to B vitamins, Sulbutiamine also has antidepressant effects and works by increasing dopamine, glutamate and acetylcholine in the brain. These effects works to reduce anxiety and to oppose fatigue.

Piracetam vs. Aniracetam vs. Noopept vs. Phenylpiracetam

Piracetam is a good place to start, but there are other nootropics that may end up being more powerful mood enhancers and may be somewhat more effective in treating depression.

Aniracetam is known at Piracetam’s big brother and is more powerful. It is about 5 times more concentrated than Piracetam and works in a slightly different manner. Aniracetam stimulates AMPA receptors that mediate synaptic transmission in the brain and, in some people, may more effectively boost serotonin and dopamine levels.

Another relative of Piracetam that you may consider is Phenylpiracetam. This nootropic has a slightly modified structure reported to make it as much as 60 times more powerful than Piracetam.

Noopept is another nootropic that has been shown to benefit people with depression and anxiety. It is far more powerful than Piracetam, estimated 1000 times, and should not be taken by those who have never before taken nootropics.


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