Stacking Piracetam with DMAE Bitartrate Dosages, Effects and Side Effects
As far as nootropic’s go, they don’t come much better than Piracetam. The product is truly great on its own, but delivers even better levels of memory and focus when used in a stack. One of the most common ways to stack Piracetam is with a source of Choline. This delivers the aforementioned boosts, whilst also clearing up the headaches that some users experience with nootropics. It is Choline that acts as the precursor to acetylcholine neurotransmitters in the brain, which can then be activated with the use of Piracetam. Click here to buy Piracetam online.
The market is filled to brimming with Choline supplements, but it is generally accepted that straight Choline is not that effective as it tends to get broken down in the intestines. This makes the path to the brain virtually impossible. A better option is an acetylcholine supplement called DMAE, as it is protected from bacteria in the enzymes. This leads us to the question of how well DMAE performs when used in a stack with Piracetam.
Using DMAE with Piracetam
DMAE, or Dimethylaminoethanol to give it the full name, is a naturally occurring substance that is found is seafoods such as squid and sardines. It is believed to have nootropic qualities that allow it to boost concentration and reduce the effects of stress. People who regularly use DMAE report having an improved mood as a result. Since it is not degraded in the stomach, DMAE acts as a good source of Choline, which means there is plenty left over to reach the brain and make the acetylcholine neurotransmitter.
When it reaches the brain, DMAE is methylated and acts as a precursor to acetylcholine. It can also act as a choline replacement and generate phosphatidyl-dimethylaminoethanol, which then becomes incorporated into cell membranes. The brain cells are then better maintained and have increased neuronal fluidity. There is also the possibility that communication in the brain may be enhanced. Recent studies have called into question the model that shows DMAE converting into acetylcholine, which means there is still a lot of debate on the subject still going on.
2-oxo-1-pyrrolidine acetamide is the full chemical name given to Piracetam, which is a nootropic supplement. While it is a derivative of Gamma-Aminobutyric acid (GABA), it has little to no effect on GABA in the brain. Piracetam is effective at modulating receptors for the acetylcholine neurotransmitters, leading to a boost in the level of activity. Piracetam is often prescribed to treat muscle twitches known as myoclonus, but it has also become popular as a dietary supplement. Read User Reviews of Piracetam here.
Fluid intelligence is thought to be given a boost when Piracetam is taken. That results in better memory and improvement in recall. User reviews often mention that they felt a better sense of mental clarity when using Piracetam. When the supplements are taken, they deliver an increase in blood flow to the brain, and they can also help facilitate communication between both sides of the brain. When that happens, creative thought is improved, as is the ability to solve problem and think laterally. According to studies, Piracetam has also proven effective in improving mood and decreasing anxiety, which in turn leads to a feeling of being more focused.
Why Stack Nootropics?
When you combine a number of different dietary supplements that deliver complimentary effects, you have created a stack. It is now possible to buy those stacks pre-assembled, with Onnit’s “Alpha Brain” the prime example of a good stack. A cheaper way to go is to create your own stack, which can be done with a little bit of experimentation.
It’s best to choose supplements that complement one another and bring out the best in each other. You can also create stacks by mixing supplements that have a distinct mechanism of action, as this usually means even more benefits to the user. When DMAE is added to Piracetam, it is to provide a source of Choline to improve the benefits of the Piracetam.
A 2-week study performed on college students showed that Piracetam was effective in boosting memory and concentration. It is fair to conclude that more nootropic benefits have been found in Piracetam than in DMAE. Piracetam has also proven to beneficial in treating aphasia as a result of a stroke, vertigo, sickle cell anemia, and dyslexia, to name but a few. It can also help fight apoxia, a deficiency of oxygen in tissues, and arrhythmia, which is an irregular heartbeat issue. This is a supplement that is neuroprotective, which means it helps keep the brain feeling young and healthy as you age. Check out our complete guide on the best way to take Piracetam.
Benefits of the Piracetam DMAE Bitartrate Combo
When used alone, the benefits of DMAE are said to range from a boost in memory and mood to a reduction in stress and anxiety. There have been studies performed that back up those claims, but many feel that it is only useful in those who are in some way impaired. Online reviewers claim that it has helped them with the concentration levels, but there have been no studies performed that would prove those claims to be valid.
What is known for sure is that it helps patients with ADHD, which may in fact prove that the concentration claims are indeed correct. Where DMAE failed to impress in studies was when it was used in patients suffering from Alzheimer’s disease and Huntington’s. No memory benefits were found when it was given to those patients.
DMAE as a Source of Choline
It is believed that by combining Piracetam with DMAE, the Choline in the latter will result in higher levels of acetylcholine that will boost the performance of the Piracetam. DMAE can be compared to a propellant being added to a wood fire. The fire would burn nicely enough on its own, but add a splash of gasoline and you will get a fire that burns brighter and stronger. Piracetam can do more when that propellant is added to the mix. Neuroscience research has brought into question the effectiveness of DMAE, which is why the latest studies have been focused on Centrophenoxine, which is a DMAE derivative with a higher potency level. User reviews and studies point to the fact that Centrophenoxine is indeed effective, especially when stacked with Piracetam. If you are unhappy with the results of your DMAE Piracetam stack, you may consider replacing DMAE with Centrophenoxine.
Proper Stack Dosage and Ratio
When stacking Piracetam with DMAE, the recommended ratio is 10:1, which means a 2,000 mg dose of Piracetam would require 200 mg of DMAE when you stack. If you are taking a larger dose of Piracetam, you might be better suited to go with a 20:1 ratio. This is because the recommended daily dose of DMAE tops of at 500 mg. A little bit of trial and error may be required to get the perfect ratio, as there are still no that many people who use this combination, which means a lack of documentation on the subject.
There are other alternatives to the Piracetam DMAE stack, with the likes of CDP Choline, Alpha GPC, and Hydergine often used in place of DMAE. It is recommended that you do your due diligence before you stack in order to find the combination that works best for you. Despite the fact that evidence suggests DMAE is not the best option there are plenty of people out there who swear by its efficacy, although no two people can expect the exact same results. While you are likely to be tempted to start your stacking experimentation right now, it is advised that you consult with your doctor before taking that next step. They can help you figure out the perfect dose for your age, height, health, etc.
There do not tend to be any major side effects with DMAE, but there is the possibility of insomnia, headaches, confusion, vivid dream, and/or constipation. Little is known hoe DMAE affects women who are pregnant or breastfeeding, so it is recommended that women in those conditions do not take it. Schizophrenia patients should also steer well clear of DMAE.
There are very few known side effects that come with Piracetam, but some users have claimed to suffer from headaches, irritability, insomnia, and anxiety. A research trial that was conducted over a 12 week period showed that there were no negative side effects to be found in those taking the Piracetam. The one side effect that may be experienced are mild headaches. The headaches are believed to come from the lack of acetylcholine in the brain, which can be overcome by taking Piracetam with a good source of Choline. If headaches are an issue when taking the supplement, they can usually be remedied by going with a Piracetam DMAE stack.