Piracetam Drug Information, Pharmacology, and Research Studies

piracetam drug

Scientists have been fascinated with the mechanism of action for the Piracetam drug since it was first discovered back in 1964. Back then, Piracetam had the distinction of being the first developed Nootropic supplement, and was produced as a GABA derivative. It was a Romanian scientist who invented the compound by converting 2-pyrrolidinone into an amide. Despite the fact that the drug has been researched heavily in its 50 years of existence, there is still a lot that neuroscientists do not know about it and how it works. Chief among those questions being asked concern the mechanism of action and the effects that it has on cognitive behavior. Click here to buy Piracetam online.

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Piracetam Drug Review:

While Piracetam is most used as a cognitive enhancing supplement, it does have some practical uses in the medical world. It was the first member of the racetam family of Nootropics, and was discovered back in 1964. The racetam supplements that came after Piracetam have all proven to be a bit more powerful than their predecessor, yet it is the original that remains the most popular of the bunch to this day.

Piracetam has proven effective in a number of different areas, such as memory performance, analytical skills, concentration, and even learning capacity. It has also shown that it can be protective of certain neuron functions and can offer a layer of protection from certain types of damage. It is for these reasons, and many more besides, that Piracetam remains the most popular Nootropic choice in North America.

Piracetam Research

Researchers and scientists are still pretty divided when it comes to talking about the drug Piracetam’s mechanism of action. All of the theories that have been put forth so far have some evidence as being correct through laboratory trials. What this may suggest is that there are actually more than one different mechanisms of action present when Piracetam goes to work.

While no specific method has been pinpointed yet, what is known is that the supplement is incredibly effective at penetrating the blood-brain barrier. Once it gains a foothold in the central nervous system, it can then influence neuronal and vascular functions without any type of adverse effects.

One effect of Piracetam that everyone can agree on is its ability to increase the permeability of neurons in the cerebral cortex. Essentially, the supplement adheres to the cell walls, granting easier access to nutrients and creating an easy exit for waste products. Research has shown the increased flow of blood and oxygen in certain parts of the brain, which means more cell building blocks are in place and can deliver a greater output of energy.

Another benefit of that is improved cell maintenance, which includes the prevention of toxin accumulation, which is often tied to the aging process. Neuronal fluidity is also increased, leading to a cell signal transmission that is greatly improved. That means improved cerebral functions of the basic variety, and may explain why Piracetam is now widely regarded as being the supplement of choice for those look to improve memory, learning ability, and other cognitive functions.

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Medical Uses for Piracetam

Another benefit of Piracetam as a drug is the effect that it has on the acetylcholine neurotransmitter. This is the transmitter responsible for the forming of memories, learning ability, focus, and attention. When it comes to fluid intelligence, it would appear that acetylcholine is needed to help with memory capacity. Read User Reviews of Piracetam here.

When talking about fluid intelligence, we are talking about the ability to recognize patterns, perform critical analysis, and make connections between abstract concepts. AMPA receptors within the brain are also believed to be modulated when Piracetam is added to the mix. The pathways found there are the ones that play a major part of the process that your brain undertakes when dealing with the storage of memories in the short and long term.

Treating Alzheimer’s and Dementia

Piracetam has some benefits that can be applied to a number of ailments, but it’s most common medical use is definitely as a tool to improve brain function in patients suffering from brain damage and degeneration. It works to relieve stress on the brain caused by drug and alcohol abuse. There are even people who claim that it’s the hangover cure to beat all others. Neuroscientists are cautiously optimistic about Piracetam’s ability to help with the treatment of Alzheimer’s disease and dementia.

A common thread among Alzheimer’s patients is that they tend to have low levels of acetylcholine activity on the brain, making it hard for them to recover memories and form new ones. By boosting Choline, a precursor to acetylcholine, Piracetam may end up preventing or reducing signs of Alzheimer’s.
Areas of the brain that have been damaged may see their membrane properties altered with the use of Piracetam. The supplement is commonly used medically on patients who have suffered a stroke or who are showing potential signs of stroke. It is believed that Piracetam reduces the risk of stroke, whilst also helping lessen the damage to the brain after a stroke. It is also used in other therapies when an effective anti-coagulant or anti-thrombotic agent is needed.

Drug Interactions and Pharmacology

Supplements really don’t come much safer than Piracetam, which has almost zero drug interactions or side effects to speak of. The side effects that do exist are generally very mild, and usually only show up when very high doses are taken. Headaches, nausea, insomnia, fatigue, gastrointestinal issues, and depression are the most common side effects. Should any of these occur when you are taking Piracetam, you can usually alleviate them by adding a Choline supplement into the mix. Check out our complete guide on the best way to take Piracetam.

Another reason why Piracetam has become so popular is because of its ability to be easily stacked with other Nootropics for greater benefits. When used in combination with these Nootropics, Piracetam has shown that it can indeed amplify the effects that come when using each supplement individually. One of the best ways to start stacking is to combine Piracetam with a Choline source such as CDP Choline or Alpha GPC. If you are someone that suffers from stress or anxiety, you may benefit from creating a stack using Aniracetam. If you are looking to sharpen your overall focus, Piracetam and Noopept tend to make an excellent stack.

Piracetam In Review

There really is no compound quite like Piracetam. The properties that it delivers are astounding, causing the scientists who discovered it back in the 1960’s to create a new category called Nootropics. The fascination with the supplement still rages on, as there are still many questions about it that continue to remain unanswered. What is known is that Piracetam works. You need only look at the positive user reviews to see that it delivers a number of benefits to the brain. There is still some debate as to the mechanism of action for Piracetam, but all people really care about is that it works as advertised. If you feel that your focus, concentration, or memory could use a boost, try Piracetam and see how it can help with all of that and more.


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