Sunifiram Powder: How to Use + Stacks

sunifiram powder

Sunifiram powder (DM-235) has a chemical makeup of 1-benzoyl-4-propanoylpiperazine. Sunifiram is an ampakine derived from pipirezine. It appears to be more than 1000 time as powerful as Piracetam. The molecular structure of Sunifiram differs from Piracetam only by having a piperazine structure instead of a pyrrolidine structure. Click here to buy Sunifriam online.

As similar as Sunifiram is to racetam nootropics in terms of both its benefits and its safety profile, it does not technically belong to that group of substances. Structurally speaking, Sunifiram is more closely related to other nootropics such as Sapunifiram (MN-19) and Unifiram.

Sunifiram10 mg x 90 capsules
By Nootropics
$24.99 ($0.28 / dose)
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What does Sunifiram Powder Do?

Users find that Sunifiram works to enhance long term potentiation, which is the process by which information is store in long term memory. Long term potentiation is considered to be a somewhat unusual benefit among nootropics. Sunifiram is a powerful Ampakine and as such is also able to increase mental stimulation, heighten alertness and sharpen focus, while also improving learning and memory as a result of its Acetylcholine stimulating properties. Overall, the strength and diverse cognitive effects offered by Sunifiram make this supplement an incredible popular new member of brain research chemicals.

Sunifiram is also derived from Piracetam but does not technically belong to the Racetam class of supplements because of its chemical structure. Sunifiram is considered an ampakine and works partiy by increasing the activity of the glycine receptor in regards to NDMA. Read User Reviews of Sunifriam here.

Mechanism of Action

Sunifiram is a piperazine alkaloid that is similar in molecular structure to both Unifiram and Sapunifiram. In one study conducted over twelve days, Sunifiram was shown to improve activity of NDMA receptors. Sunifiram powder goes on to demonstrate significant improvement in the activities of both AMPA receptors and Acetylcholine (ACh) receptors.

The structure of Sunifiram is quite similar to Piracetam, however it does have one major difference. Sunifiram has a pyrrolidine backbone with a piperazine structure attached to it and left open.

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Sunifiram and Unifiram

A combination of Sunifiram with Unifiram powder was shown in one study to help boost the levels of Acetylcholine to the prefrontal cortex of lab animals. It also showed an anti-amnesiac effect. Evidence from the study suggests the effects of Sunifiram on the AMPA receptors may be the action that causes this.

In another study Sunifiram was shown to help boost the long term potentiation of mice that had undergone a bulbectomy, a procedure in which the part of the brain responsible for the sense of smell, known as the olfactory bulb, removed. Sunifiram has also been shown to be able to improve short term memory assessment.

Sunifiram does not, however, show any signs of being able to reduce symptoms of depression. Check out our complete guide on the best way to take Sunifriam.

How to Take Sunifiram Powder

The suggested dose of Sunifiram is very small, only 7mg, and it can be split up and taken two to three times within a day. This smart drug is available in capsules, bulk powder, and tablet forms. Evidence suggests that Sunifiram may be able to produce improvements long term memory and the brain’s ability to use Acetylcholine. This nootropic works by targeting and stimulating the receptors for AMPA and NDMA Glutamine. This makes Sunifiram an outstanding choice as a nootropic to use alone, rather than part of a stack the way many other nootropics are used.

There is still a lot that science has yet to figure out about the brain and how it functions, and how these types of chemicals affect the brain. For this reason, it is nearly impossible to determine how a given nootropic will affect a specific individual. It all depends on that person’s individual brain chemistry, their natural cognitive ability and their lifestyle. There are a few places where you can buy Sunifiram powder online, but this is still a relatively new nootropics in the USA.


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